Zu "2165340-32-7" wurden 2 Artikel gefunden!
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CU-CPT-9a
Artikelnummer: TGM-T7317-100mg
Description: CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-. Target: TLR. Smiles: COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1. References: Zhang S , Hu Z , Tanji H , et al. Small-molecule inhibition of TLR8 through...
| Anwendung: | TLR8 antagonist |
| CAS | 2165340-32-7 |
| MW: | 265.31 D |
ab 34,00 €
CU-CPT9a
Artikelnummer: Cay28722-1
CU-CPT9a is an antagonist of toll-like receptor 8 (TLR8). It inhibits activation of NF-kappaB induced by the TLR8 agonist R-848 (Cay-14806) in TLR8-overexpressing HEK-Blue cells (IC50 = 0.5 nM). CU-CPT9a reverses R-848-induced increases in NF-kappaB p65, IRAK-4, and TRAF3 protein levels in HEK-Blue cells.Formal...
| Schlagworte: | 4-(7-methoxy-4-quinolinyl)-2-methyl-phenol |
| Anwendung: | TLR8 antagonist |
| CAS | 2165340-32-7 |
| MW: | 265.3 D |
ab 43,00 €
