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I-CBP112 hydrochloride
I-CBP112 hydrochloride

Artikelnummer: TGM-T4247-100mg

Description: I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly reduced the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells...
Anwendung: CBP and EP300 inhibitor
CAS 2147701-33-3
MW: 505.05 D
ab 83,00 €
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I-CBP112 (hydrochloride)
I-CBP112 (hydrochloride)

Artikelnummer: Cay14468-1

I-CBP112 is an inhibitor of p300 and CREB-binding protein (CBP) histone acetyltransferases. It binds to the p300 and CBP bromodomains (Kds = 167 and 151 nM, respectively) and is selective for p300 and CBP over BRD4, as well as a panel of 104 nuclear receptors and ion channels and a panel of 32 enzymes at 10 µM....
Schlagworte: 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-1-propanone,...
Anwendung: CBP and EP300 inhibitor
CAS 2147701-33-3
MW: 505.1 D
ab 61,00 €
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