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PD0166285 dihydrochloride
Artikelnummer: TGM-T6931L-1mg
Description: PD-166285 is an effective and broadly active inhibitor of protein tyrosine kinase. Target: Others. Smiles: O=C1C(C2=C(C=CC=C2Cl)Cl)=CC3=C(N1C)N=C(NC4=CC=C(C=C4)OCCN(CC)CC)N=C3.Cl.Cl. References: Leijen S, Beijnen JH, Schellens JH. Abrogation of the G2 checkpoint by inhibition of Wee-1 kinase results in...
| Schlagworte: | PD-166285 |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 212391-63-4 |
| MW: | 585.35 D |
91,00 €
PD 166285
Artikelnummer: Cay26804-5
PD 166285 is a tyrosine kinase inhibitor. It inhibits Src, FGFR1, EGFR, and PDGFRbeta (IC50s = 8.4, 39.3, 87.5, and 98.3 nM, respectively), as well as WEE1 (IC50 = 24 nM). PD 166285 inhibits PDGF- or EGF-induced receptor autophosphorylation in vascular smooth muscle cells (VSMCs) and A431 cells, respectively, and...
| Schlagworte: | 6-(2,6-dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one, dihydrochloride |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 212391-63-4 |
| MW: | 585.4 D |
ab 50,00 €
