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WHI-P180
Artikelnummer: TGM-T2032-100mg
Description: WHI-P180 (Janex 3) is a potent inhibitor of EGFR and Cdk2, with IC50 values of 4.0 µM and 1.0 µM, respectively. Target: CDK, EGFR, c-RET, VEGFR. Smiles: COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC. References: An R, et al. Pharm Res. 2009 Feb,26(2):449-58.
| Schlagworte: | Janex 3 |
| CAS | 211555-08-7 |
| MW: | 297.31 D |
ab 40,00 €
WHI-P180
Artikelnummer: Cay23452-5
WHI-P180 is a multi-kinase inhibitor with IC50 values of 4.5 and 66 nM for the human proto-oncogene RET and kinase insert domain receptor (KDR), respectively. It also inhibits EGFR (IC50 = 4 µM) and binds to tau-tubulin kinase 1 (TTBK1, Kds = 0.46 and 0.24 µM for phosphorylated and non-phosphorylated TTBK1,...
| Schlagworte: | Janex 3, 3-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 211555-08-7 |
| MW: | 297.3 D |
ab 128,00 €
