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Lucitanib (hydrochloride)
Artikelnummer: Cay37711-1
Lucitanib is a dual inhibitor of VEGFR and FGFR that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50s = 7, 25, and 10 nM, respectively) and FGFR1 and FGFR2 (IC50s = 17.5 and 82.5 nM, respectively). It is selective for these receptors over FGFR3 and FGFR4 (IC50s = 237.5 and >1,000 nM, respectively), as well as the PDGFR...
| Schlagworte: | AL 3810, E-3810, 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxy-4-quinolinyl]oxy]-N-methyl-1-naphthalenecarboxamide,... |
| Anwendung: | VEGFR / FGFR dual inhibitor |
| CAS | 2108875-91-6 |
| MW: | 516.4 D |
ab 47,00 €
