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GSK-J2 (sodium salt)
Artikelnummer: Cay12056-1
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J2 is a pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 (IC50 > 100 µM), making it an appropriate negative control...
| Schlagworte: | 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-3-yl)pyrimidin-4-yl)amino)propanoic acid, monosodium salt |
| Anwendung: | H3K27 HDAC inhibitor |
| CAS | 2108665-15-0 |
| MW: | 412.4 D |
ab 49,00 €
