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Gemcitabine elaidate
Artikelnummer: TGM-T15378-2mg
Description: Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active...
| Schlagworte: | Gemcitabine 5'-elaidate, CP-4126, Gemcitabine (elaidate), CO-101 |
| Anwendung: | Targets ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] (RRM1) |
| CAS | 210829-30-4 |
| MW: | 527.64 D |
ab 297,00 €
Gemcitabine Elaidate
Artikelnummer: Cay28303-1
Gemcitabine elaidate is a lipophilic prodrug form of the nucleoside analog gemcitabine (Cay-11690, Cay-9003096) that contains an elaidic acid (Cay-90250) moiety. Gemcitabine elaidate inhibits growth of gemcitabine-sensitive L1210/L5, BCLO, and A2780 cells (IC50s = 0.0033, 0.0042, and 0.0025 µM, respectively) but not...
| Schlagworte: | CP 4126, 2'-deoxy-2',2'-difluoro-cytidine, 5'-(9E)-9-octadecenoate |
| Anwendung: | Lipophilic gemcitabine prodrug, antineoplastic, antimetabolite |
| CAS | 210829-30-4 |
| MW: | 527.6 D |
ab 44,00 €
