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MCC950
Artikelnummer: TGM-T3701-100mg
Description: CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1beta secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically...
| Schlagworte: | CP-456773 |
| Anwendung: | NLRP3 inhibitor |
| CAS | 210826-40-7 |
| MW: | 404.48 D |
ab 42,00 €
MCC950
Artikelnummer: Cay17510-1
MCC950 is an inhibitor of NOD-like receptor protein 3 (NLRP3) inflammasome activation. It inhibits ATP-induced IL-1beta release in LPS-primed mouse bone marrow-derived macrophages (BMDMs, IC50 = 7.5 nM), as well as cytosolic LPS-induced IL-1beta release in Pam3CSK4-primed mouse BMDMs at 0.1 and 1 µM, indicating...
| Schlagworte: | CP 456,773, N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide |
| Anwendung: | NLRP3 inhibitor |
| CAS | 210826-40-7 |
| MW: | 404.5 D |
ab 109,00 €
