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N-Butyldeoxynojirimycin (hydrochloride)
Artikelnummer: Cay21065-1
NB-DNJ is an iminosugar that inhibits UDP-glucose ceramide glucosyltransferase and beta-glucosidase 2 (IC50s = 32 and 81 µM, respectively, for the rat recombinant enzymes). It also increases the activity of wild-type acid beta-glucosidase, as well as the S364R, N370S, V15M, or M123T mutants, in COS-7 cells...
| Schlagworte: | Miglustat, NB-DNJ, 1-butyl-2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol, monohydrochloride |
| Anwendung: | Glucosylceramide synthase inhibitor |
| CAS | 210110-90-0 |
| MW: | 255.7 D |
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