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BRD4 degrader AT1
Artikelnummer: TGM-T5439-5mg
Description: BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells. Target: Epigenetic Reader Domain, PROTACs. Smiles:...
| Anwendung: | BRD4 degradation driving PROTAC |
| CAS | 2098836-45-2 |
| MW: | 972.68 D |
1.099,00 €
AT-1
Artikelnummer: Cay33265-1
AT-1 is a proteolysis-targeting chimera (PROTAC) that contains the bromodomain and extra terminal (BET) domain-containing protein inhibitor (+)-JQ1 (Cay-11187) conjugated to PROTAC building block VH ligand 032 (Cay-39982). It selectively degrades bromodomain-containing protein 4 (BRD4) over BRD3 and BRD2 in HeLa...
| Schlagworte: | (4R)-N-acetyl-3-[[6-[[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]... |
| Anwendung: | BRD4 degradation driving PROTAC |
| CAS | 2098836-45-2 |
| MW: | 972.7 D |
ab 65,00 €
