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MBQ-167
MBQ-167

Artikelnummer: TGM-T16021-100mg

Description: MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively). Target: Ras, CDK. Smiles: CCn1c2ccccc2c2cc(ccc12)-n1nncc1-c1ccccc1. References: Humphries-Bickley T, et al. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic...
Anwendung: Rac / Cdc42 dual inhibitor
CAS 2097938-73-1
MW: 338.41 D
ab 31,00 €
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MBQ-167
MBQ-167

Artikelnummer: Cay35437-5

MBQ-167 is a dual inhibitor of Rac and cell division cycle 42 (Cdc42, IC50s = 103 and 78 nM, respectively). It reduces Rac and Cdc42 GTP binding and GTPase activity and limits migration and mammosphere formation in MDA-MB-231 breast cancer cells when used at a concentration of 250 nM. MBQ-167 (250 nM), alone and in...
Schlagworte: 9-ethyl-3-(5-phenyl-1H-1,2,3-triazol-1-yl)-9H-carbazole
Anwendung: Rac / Cdc42 dual inhibitor
CAS 2097938-73-1
MW: 338.4 D
ab 41,00 €
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