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OATD-01
Artikelnummer: TGM-T9592-100mg
Description: OATD-01 is a highly active inhibitor of both Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase). Target: Others. Smiles: C[C@H]1CN([C@@H](Cc2ccc(Cl)cc2)CO1)C1CCN(CC1)c1nc(N)n[nH]1. References: Robert Koralewski, et al. Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential...
| Anwendung: | CHIT1 / CHIA inhibitor |
| CAS | 2088453-21-6 |
| MW: | 390.91 D |
ab 52,00 €
OATD-01
Artikelnummer: Cay35193-1
OATD-01 is an inhibitor of chitotriosidase 1 (CHIT1) and acidic mammalian chitinase (CHIA), also known as AMCase (IC50s = 23 and 9 nM, respectively). It is selective for CHIT1 and CHIA over a panel of 98 enzymes at 10 µM. OATD-01 (30 and 100 mg/kg) reduces the degree of lung fibrosis and plasma chitinolytic activity...
| Schlagworte: | 5-[4-[(2S,5S)-5-[(4-chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-1H-1,2,4-triazol-3-amine |
| Anwendung: | CHIT1 / CHIA inhibitor |
| CAS | 2088453-21-6 |
| MW: | 390.9 D |
ab 53,00 €
