Zu "2002381-31-7" wurden 2 Artikel gefunden!
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APS-2-79 hydrochloride
Artikelnummer: TGM-T6760-100mg
Description: APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK. Target: MEK, MAPK. Smiles:...
| Schlagworte: | APS-2-79, APS-2-79 HCl |
| Anwendung: | KSR-dependent MAPK signaling modulator |
| CAS | 2002381-31-7 |
| MW: | 423.89 D |
ab 38,00 €
APS-2-79 (hydrochloride)
Artikelnummer: Cay22137-5
APS-2-79 is an inhibitor of MAPK signaling dependent on kinase suppressor of Ras (KSR). It inhibits ATPbiotin binding to KSR2 in KSR2-MEK1 complexes (IC50 = 120 nM), stabilizes KSR2 in an inactive state, and reduces interactions between B-RAF and KSR2-MEK1 complexes. APS-2-79 (5 µM) inhibits KSR-stimulated...
| Schlagworte: | 6,7-dimethoxy-N-(2-methyl-4-phenoxyphenyl)-4-quinazolinamine, monohydrochloride |
| Anwendung: | KSR-dependent MAPK signaling modulator |
| CAS | 2002381-31-7 |
| MW: | 423.9 D |
ab 45,00 €
