Zu "198474-05-4" wurden 2 Artikel gefunden!
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PF-06840003
Artikelnummer: TGM-T4307-100mg
Description: PF-06840003 (EOS200271) is a specific and orally active IDO-1 inhibitor. Target: IDO, Indoleamine 2,3-Dioxygenase (IDO). Smiles: Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1. References: Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune...
| Schlagworte: | EOS200271, PF 06840003 |
| Anwendung: | IDO-1 inhibitor |
| CAS | 198474-05-4 |
| MW: | 232.21 D |
ab 38,00 €
EOS200271
Artikelnummer: Cay25003-5
EOS200271 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1, IC50 = 0.15 µM for the human enzyme). It is selective for IDO-1 over IDO-2 up to a concentration of 200 µM for the human recombinant enzymes. EOS200271 inhibits IDO-1-mediated production of kynurenine induced by IFN-gamma in HeLa cells (IC50 = 1.8...
| Schlagworte: | PF-06840003, 3-(5-fluoro-1H-indol-3-yl)-2,5-pyrrolidinedione |
| Anwendung: | IDO-1 inhibitor |
| CAS | 198474-05-4 |
| MW: | 232.2 D |
ab 35,00 €
