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Bay 11-7085
Artikelnummer: TGM-T1934-100mg
Description: Bay 11-7085 can irreversibly inhibit the IkappaBalpha phosphorylation induced by TNFalpha (IC50: 10 µM). Target: NF-kappaB, IkappaB/IKK, Apoptosis, Ferroptosis. Smiles: CC(C)(C)c1ccc(cc1)S(=O)(=O)\C=C\C#N. References: Pierce JW, et al. J Biol Chem. 1997, 272(34), 21096-21103.
| Schlagworte: | BAY 11-7083 |
| Anwendung: | Irreversible IkappaBalpha phosphorylation inhibitor |
| CAS | 196309-76-9 |
| MW: | 249.33 D |
ab 31,00 €
BAY 11-7085
Artikelnummer: Cay14795-5
In the classical pathway of NF-kappaB activation, phosphorylation of the inhibitor of NF-kappaB (IkappaBalpha) releases the inhibitor from NF-kappaB, allowing IkappaBalpha degradation and NF-kappaB activation and nuclear import. BAY 11-7085 is an irreversible inhibitor of IkappaBalpha phosphorylation, preventing...
| Schlagworte: | 3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2E-propenenitrile |
| Anwendung: | Irreversible IkappaBalpha phosphorylation inhibitor |
| CAS | 196309-76-9 |
| MW: | 249.3 D |
ab 77,00 €
