Zu "1956370-21-0" wurden 2 Artikel gefunden!
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RIPA-56
Artikelnummer: TGM-T7795-100mg
Description: RIPA-56 is an inhibitor of RIP1. Target: RIP kinase. Smiles: CCC(C)(C)C(=O)N(O)Cc1ccccc1. References: Ren Y , Su Y , Sun L , et al. Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response...
| Anwendung: | RIPK1 inhibitor |
| CAS | 1956370-21-0 |
| MW: | 221.3 D |
ab 33,00 €
RIPA-56
Artikelnummer: Cay33431-10
RIPA-56 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1, IC50 = 13 nM). It is selective for RIPK1 over RIPK3 at 10 µM, as well as over a panel of additional kinases at 2 µM. RIPA-56 inhibits Z-VAD-FMK-induced necrosis in HT-29 cells (EC50 = 28 nM). In vivo, RIPA-56 (6 mg/kg) reduces...
| Schlagworte: | N-hydroxy-2,2-dimethyl-N-(phenylmethyl)-butanamide |
| Anwendung: | RIPK1 inhibitor |
| CAS | 1956370-21-0 |
| MW: | 221.3 D |
ab 84,00 €
