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Rimiducid
Artikelnummer: TGM-T14298-100mg
Description: Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-linking the FKBP domains. It dimerizes the Caspase 9 suicide switch and rapidly induces...
| Anwendung: | Targets caspase 9 [EC:3.4.22.62] (CASP9) |
| CAS | 195514-63-7 |
| MW: | 1411.63 D |
ab 135,00 €
Rimiducid
Artikelnummer: Cay35303-1
Rimiducid is a chemical inducer of dimerization (CID) for fusion proteins of the FK506 binding protein (FKBP) mutant FKBPF36V. It selectively binds to FKBPF36V over wild-type FKBP (IC50s = 0.005 and >10 µM, respectively). Rimiducid induces apoptosis in HT-1080 fibrosarcoma cells expressing a FKBPF36V fusion protein...
| Schlagworte: | AP1903, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylic acid,... |
| Anwendung: | FKBPF36V fusion protein chemical inducer of dimerization (CID) |
| CAS | 195514-63-7 |
| MW: | 1411.6 D |
ab 105,00 €
