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MAK683
MAK683

Artikelnummer: TGM-T15201-100mg

Description: MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay). Target: Histone Methyltransferase. Smiles: Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12. References: Chan, Ho Man, et al. TRIAZOLOPYRIMID INECOMPOUNDS AND USES THEREOF....
Anwendung: PRC2 (polycomb repressive complex 2)-mediated H3K27 trimethylation inhibitor
CAS 1951408-58-4
MW: 376.39 D
ab 48,00 €
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MAK-683
MAK-683

Artikelnummer: Cay29316-1

MAK-683 is an inhibitor of trimethylation of histone 3 lysine 27 (H3K27) by polycomb repressive complex 2 (PRC2), a complex that includes embryonic ectoderm development protein (EED). MAK-683 has an IC50 value of 5.9 nM in an EED-H3K27me3 peptide competition binding assay and inhibits H3K27 trimethylation in G401...
Schlagworte: N-[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
Anwendung: PRC2 (polycomb repressive complex 2)-mediated H3K27 trimethylation inhibitor
CAS 1951408-58-4
MW: 376.4 D
ab 109,00 €
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