Zu "1950634-92-0" wurden 3 Artikel gefunden!
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dBET6
Artikelnummer: TGM-T5130-100mg
Description: dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity. Target: Apoptosis, Epigenetic Reader Domain, PROTACs. Smiles: CC=1C2=C(N3C([C@H](CC(NCCCCCCCCNC(COC4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C....
| Anwendung: | Protac(R) reagent |
| CAS | 1950634-92-0 |
| MW: | 841.37 D |
ab 48,00 €
dBET6
Artikelnummer: Cay35385-25
dBET6 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4). It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ1, which binds bromo- and extra-terminal (BET) proteins, linked to thalidomide, a ligand for the E3 ubiquitin ligase...
| Schlagworte: | (6S)-4-(4-chlorophenyl)-N-[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]oct... |
| Anwendung: | BRD4 degradation driving PROTAC |
| CAS | 1950634-92-0 |
| MW: | 841.4 D |
ab 117,00 €
dBET6
Artikelnummer: BPS-82022
dBET6 is a potent, selective, and cell-permeable PROTAC connected by ligands for Cereblon and BET and has antitumor activity.
| Anwendung: | Protac(R) reagent |
| CAS | 1950634-92-0 |
| MW: | 841,4 D |
880,00 €
