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ARV-771
Artikelnummer: TGM-T5435-100mg
Description: ARV-771 is a potent BET degrader based on PROTAC technology, with Kds of 34 nM for BRD2(1), 4.7 nM for BRD2(2), 8.3 nM for BRD3(1), 7.6 nM for BRD3(2), 9.6 nM for BRD4(1), and 7.6 nM for BRD4(2), respectively[1]. Target: PROTACs, Epigenetic Reader Domain. Smiles:...
| Anwendung: | Protac(R) reagent |
| CAS | 1949837-12-0 |
| MW: | 986.64 D |
ab 55,00 €
ARV-771
Artikelnummer: Cay21299-5
ARV-771 is a proteolysis-targeting chimera (PROTAC) that drives the degradation of bromodomain and extra terminal domain (BET) family proteins. It is comprised of a BET-binding moiety conjugated via a linker to a von Hippel-Lindau (VHL) E3 ligase-binding moiety. ARV-771 induces degradation of bromodomain-containing...
| Schlagworte: | (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazep... |
| Anwendung: | PROTAC, BET family protein degradation |
| CAS | 1949837-12-0 |
| MW: | 986.6 D |
ab 78,00 €
ARV-771
Artikelnummer: BPS-82055
ARV-771 is a BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1) and BRD4(2), respectively.
| Anwendung: | Protac(R) reagent |
| CAS | 1949837-12-0 |
| MW: | 986,7 D |
901,00 €
