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KMH-233
Artikelnummer: TGM-T32404-100mg
Description: KMH-233 is a potent selective LAT1 inhibitor 1 that inhibits the uptake of LAT1 substrate, L-leucine, and cell growth. Even at low concentrations (25 µM), it significantly enhanced the efficacy of betastatin and cisplatin. Target: Others. Smiles:...
| Schlagworte: | KMH233 |
| Anwendung: | LAT1 inhibitor |
| CAS | 1941174-13-5 |
| MW: | 587.58 D |
ab 1.530,00 €
KMH-233
Artikelnummer: Cay31032-1
KMH-233 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 18.2 µM). It is selective for LAT1 over LAT2 (IC50 = >1,000 µM). KMH-233 (25 and 100 µM) reduces the viability of MCF-7 cells and enhances cell death induced by bestatin (Cay-21217, Cay-70520) or cisplatin (Cay-13119) in the same cells. It also...
| Schlagworte: | 3-[[[2,4-dicyano-3-[4-[2-(methylamino)-2-oxoethoxy]phenyl]pyrido[1,2-a]benzimidazol-1-yl]amino]carbonyl]-L-phenylalanine |
| Anwendung: | LAT1 inhibitor |
| CAS | 1941174-13-5 |
| MW: | 587.6 D |
217,00 €
