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SB 239063
Artikelnummer: TGM-T6976-100mg
Description: SB 239063 (SB239063) is a potent and selective p38 MAPKalpha/beta inhibitor with IC50 of 44 nM, showing no activity against the gamma- and delta-kinase isoforms. Target: p38 MAPK, Autophagy. Smiles: COc1nccc(n1)-c1c(ncn1[C@H]1CC[C@H](O)CC1)-c1ccc(F)cc1. References: Underwood DC, et al. J Pharmacol Exp...
| Schlagworte: | SB239063 |
| Anwendung: | p38 MAPK inhibitor |
| CAS | 193551-21-2 |
| MW: | 368.4 D |
ab 43,00 €
SB 239063
Artikelnummer: Cay19142-1
SB 239063 is a selective p38 MAPK inhibitor (IC50 = 44 nM for recombinant purified p38alpha). It displays greater than 220-fold selectivity for p38 MAPK over ERK, JNK1, and other kinases. SB 239063 has been shown to reduce inflammatory cytokine production in lipopolysaccharide-stimulated human peripheral blood...
| Schlagworte: | trans-4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]-cyclohexanol |
| Anwendung: | p38 MAPK inhibitor |
| CAS | 193551-21-2 |
| MW: | 368.4 D |
ab 50,00 €
