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Tipifarnib
Artikelnummer: TGM-T6271-10mg
Description: Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this...
| Schlagworte: | Zarnestra, R115777, IND 58359 |
| Anwendung: | Antineoplastic |
| CAS | 192185-72-1 |
| MW: | 489.4 D |
ab 34,00 €
Tipifarnib
Artikelnummer: Cay11747-5
Tipifarnib is a nonpeptidomimetic, CAAX-competitive inhibitor of farnesyltransferase (IC50 = 0.86 nM). It prevents farnesylation of Ras GTPases and has shown potent efficacy in various in vitro and in vivo tumor models.Formal Name:...
| Schlagworte: | R 115777, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone |
| Anwendung: | CAAX-competitive farnesyltransferase inhibitor, Ras GTPase farnesylation inhibitor |
| CAS | 192185-72-1 |
| MW: | 489.4 D |
ab 60,00 €
