Zu "1919888-06-4" wurden 2 Artikel gefunden!
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NEU
LY3295668
Artikelnummer: Cay27914-1
LY3295668 is an inhibitor of Aurora A kinase (IC50 = 2 phase in HeLa cells (IC50 = 108 nM). In vivo, LY3295668 (40 mg/kg per day) decreases tumor volume in a patient-derived xenograft (PDX) mouse model of small cell lung cancer.Formal Name:...
| Schlagworte: | AK-01,... |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1919888-06-4 |
| MW: | 490 D |
ab 103,00 €
LY3295668
Artikelnummer: TGM-T15815-100mg
Description: LY3295668 (AK-01) is a selective inhibitor of Aurora A, with Ki values of 0.8 nM for Aurora A and 1038 nM for Aurora B. Target: Aurora Kinase. Smiles: C[C@@H]1C[C@@](Cc2nc(Nc3cc(C)[nH]n3)ccc2F)(CCN1Cc1cccc(Cl)c1F)C(O)=O. References: Gong X, et al. Aurora-A kinase inhibition is synthetic lethal with loss...
| Schlagworte: | AK-01 |
| CAS | 1919888-06-4 |
| MW: | 489.95 D |
ab 142,00 €
