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JQEZ5
Artikelnummer: TGM-T7305-100mg
Description: JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM). Target: Histone Methyltransferase. Smiles: CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(nc2n(ncc12)C(C)C)-c1ccc(nc1)N1CCN(C)CC1. References: Xie H , Peng C , Huang J , et al. Chronic Myelogenous Leukemia- Initiating Cells Require Polycomb...
| Anwendung: | EZH2 lysine methyltransferase inhibitor |
| CAS | 1913252-04-6 |
| MW: | 542.68 D |
ab 36,00 €
JQEZ5
Artikelnummer: Cay27457-5
JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM), the enzymatic subunit of polycomb repressive complex 2 (PRC2). It inhibits colony formation of primary human CD34+ chronic myelogenous leukemia (CML) stem/progenitor cells but not non-cancerous human CD34+ hematopoietic stem/progenitor cells...
| Schlagworte: | N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1... |
| Anwendung: | EZH2 lysine methyltransferase inhibitor |
| CAS | 1913252-04-6 |
| MW: | 542.7 D |
ab 150,00 €
