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K-7174 dihydrochloride
Artikelnummer: TGM-T11742L-10mg
Description: K-7174 dihydrochloride is a proteasome and GATA inhibitor that inhibits neuronal degeneration and induces apoptosis. Target: Proteasome. Smiles: Cl.Cl.COc1cc(\C=C\CCCN2CCCN(CCC\C=C\c3cc(OC)c(OC)c(OC)c3)CC2)cc(OC)c1OC. References: Umetani M, et al. A novel cell adhesion inhibitor, K-7174, reduces the...
| Schlagworte: | K7174 2HCl, K-7174 2HCl, K 7174 2HCl |
| Anwendung: | 20S proteasome inhibitor |
| CAS | 191089-60-8 |
| MW: | 641.67 D |
ab 31,00 €
K-7174 (hydrochloride)
Artikelnummer: Cay32773-10
K-7174 is a 20S proteasome inhibitor. It inhibits the beta1, beta2, and beta5 catalytic subunits of the 20S proteasome when used at a concentration of 5 µM. K-7174 (10 µM) reduces TNF-alpha- or IL-1beta-induced adherence of U937 monocytes to human umbilical vein endothelial cells (HUVECs) in a co-culture model of...
| Schlagworte: | hexahydro-1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]-1H-1,4-diazepine, dihydrochloride |
| Anwendung: | 20S proteasome inhibitor |
| CAS | 191089-60-8 |
| MW: | 641.7 D |
ab 133,00 €
