Zu "1903008-80-9" wurden 2 Artikel gefunden!
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Lazertinib
Artikelnummer: TGM-T4485-100mg
Description: Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively. Target: EGFR. Smiles:...
| Schlagworte: | Lazertinib (YH25448), GNS-1480, YH25448 |
| Anwendung: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| CAS | 1903008-80-9 |
| MW: | 554.64 D |
ab 42,00 €
Lazertinib
Artikelnummer: Cay29670-10
Lazertinib is an irreversible inhibitor of mutant EGFRs (IC50s = 1.7, 2, and 3.3 nM for EGFRL858R/T790M, EGFRDel19/T790M, and EGFRDel19, respectively). It is selective for mutant EGFRs over wild-type EGFR, HER2, and HER4 (IC50s = 76, 364, and 1,017 nM, respectively). Lazertinib reduces viability of Ba/F3 cells...
| Schlagworte: | YH25448,... |
| Anwendung: | Mutant EGFR irreversible inhibitor |
| CAS | 1903008-80-9 |
| MW: | 554.6 D |
ab 133,00 €
