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SJA6017
Artikelnummer: TGM-T28786-1mg
Description: SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 ( IC50 = 78 nM). SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM). SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functional outcome. Target: Others. Smiles:...
| Schlagworte: | Calpain Inhibitor 4, Calpain Inhibitor VI, Calpain-In-4, SJA 6017, SJA-6017 |
| Anwendung: | Calpain-1/-2 inhibitor |
| CAS | 190274-53-4 |
| MW: | 372.45 D |
181,00 €
Calpain Inhibitor VI
Artikelnummer: Cay23942-1
Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases µ-calpain (calpain-1, IC50 = 7.5 nM) and m-calpain (calpain-2, IC50 = 78 nM). It also inhibits cathepsins B and L (IC50s = 15 and 1.6 nM, respectively). It is selective for these calpains and cathepsins over other cysteine and serine...
| Schlagworte: | SJA 6017, 2S-[[(4-fluorophenyl)sulfonyl]amino]-N-[(1S)-1-formyl-3-methylbutyl]-3-methyl-butanamide |
| Anwendung: | Calpain-1/-2 inhibitor |
| CAS | 190274-53-4 |
| MW: | 372.5 D |
100,00 €
