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Ensifentrine
Ensifentrine

Artikelnummer: TGM-T25376-100mg

Description: Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that is under clinical development for the treatment of asthma and COPD and, potentially, cystic fibrosis. Target: PDE. Smiles:...
Schlagworte: Ensifentrinum, Ensifentrina
Anwendung: Targets cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (PDE4)
CAS 1884461-72-6
MW: 477.56 D
ab 31,00 €
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Ensifentrine
Ensifentrine

Artikelnummer: Cay38761-1

Ensifentrine is a phosphodiesterase 3 (PDE3) inhibitor (IC50 = 0.4 nM). It is selective for PDE3 over PDE4 (IC50 = 1,479 nM). Ensifentrine reduces phytohemagglutinin-induced proliferation of isolated human monocytes in a concentration-dependent manner and inhibits LPS-induced increases of TNF-alpha protein levels in...
Schlagworte: RPL 554, VMX 554,...
Anwendung: PDE3 inhibitor
CAS 1884461-72-6
MW: 477.6 D
ab 41,00 €
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