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Bimosiamose
Artikelnummer: TGM-T14574-1mg
Description: Bimosiamose has anti-inflammatory effects[1]. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 µM, 20 µM, and 86 µM for E-selectin, L-selectin, and P-selectin respectively. Target: Integrin. Smiles:...
| Schlagworte: | TBC-1269 |
| Anwendung: | pan Selectin inhibitor |
| CAS | 187269-40-5 |
| MW: | 862.91 D |
ab 208,00 €
Bimosiamose
Artikelnummer: Cay30878-1
Bimosiamose is a pan-selectin inhibitor (IC50s = 88, 20, and 86 µM for E-, P-, and L-selectin, respectively). It reduces adhesion of HL-60 cells to E- and P-selectin when used at a concentration of 129 µM. In vivo, bimosiamose (200 mg/kg) reduces skin scaliness, induration, and erythema in a patient-derived...
| Schlagworte: | TBC 1269, 3',3'''-(1,6-hexanediyl)bis[6'-(alpha-D-mannopyranosyloxy)-[1,1'-biphenyl]-3-acetic acid |
| Anwendung: | pan Selectin inhibitor |
| CAS | 187269-40-5 |
| MW: | 862.9 D |
ab 114,00 €
