Zu "183321-74-6" wurden 2 Artikel gefunden!
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Erlotinib
Artikelnummer: Cay10483-250
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Schlagworte: | NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 183321-74-6 |
| MW: | 393.4 D |
ab 44,00 €
Erlotinib
Artikelnummer: TGM-T0373-100mg
Description: Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer. Target: Autophagy, EGFR. Smiles: N(C=1C2=C(C=C(OCCOC)C(OCCOC)=C2)N=CN1)C3=CC(C#C)=CC=C3. References: Chin TM, et al. Reduced Erlotinib sensitivity of epidermal growth factor...
| Schlagworte: | R1415, CP358774, OSI-744, NSC 718781 |
| CAS | 183321-74-6 |
| MW: | 393.44 D |
ab 42,00 €
