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Risdiplam
Artikelnummer: TGM-T16757-100mg
Description: Risdiplam (RO7034067) (RG7916) is orally administered. Risdiplam is a centrally and peripherally distributed SMN2 pre-mRNA splicing modifier which increases survival motor neuron (SMN) protein levels[1]. Target: DNA/RNA Synthesis. Smiles: Cc1cn2nc(cc(C)c2n1)-c1cc(=O)n2cc(ccc2n1)N1CCNC2(CC2)C1....
| Schlagworte: | RO7034067, RG7916 |
| Anwendung: | Targets survival motor neuron protein (SMN) |
| CAS | 1825352-65-5 |
| MW: | 401.46 D |
ab 55,00 €
Risdiplam
Artikelnummer: Cay29028-5
Risdiplam is a survival of motor neuron-2 (SMN2) splicing modifier. It enhances SMN2 splicing (EC1.5x = 40 nM) and increases SMN protein levels (EC1.5x = 163 nM) in cellular assays. Risdiplam (3 mg/kg) increases brain and quadricep muscle SMN protein levels in the adult C/C-allele mouse model of mild spinal muscular...
| Schlagworte: | RG-7916, RO7034067,... |
| Anwendung: | SMN2 splicing modifier |
| CAS | 1825352-65-5 |
| MW: | 401.5 D |
ab 52,00 €
