Zu "1825345-33-2" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
AZ9482
Artikelnummer: Cay30292-5
AZ9482 is a poly(ADP-ribose) polymerase (PARP) inhibitor (IC50s = 1, 1, 46, 640, 9, and 160 nM for PARP1, -2, -3, -6, TNKS1/PARP5a, and TNKS2, respectively). It induces centrosome declustering (EC50 = 50 = 3 nM).Formal Name:...
| Schlagworte: | 2-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinecarbonitrile |
| Anwendung: | PARP inhibitor |
| CAS | 1825345-33-2 |
| MW: | 450.5 D |
ab 94,00 €
AZ9482
Artikelnummer: SYN-3046-M001
AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also showed a 3nM GI50 in the DLBCL cell line OCI-LY-19 in a 3-day AlamarBlue assay. Consistent with...
| Schlagworte: | 2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile |
| Anwendung: | Potent, selective PARP inhibitor |
| CAS | 1825345-33-2 |
| MW: | 450.5 D |
ab 139,00 €
AZ9482
Artikelnummer: TGM-T22264-100mg
Description: AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells. Target: PARP. Smiles: O=C(N1CCN(CC1)c1ncccc1C#N)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1....
| Anwendung: | PARP inhibitor |
| CAS | 1825345-33-2 |
| MW: | 450.49 D |
ab 52,00 €
