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SB225002
Artikelnummer: TGM-T1955-100mg
Description: SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2. Target: CXCR. Smiles: N(C(NC1=C(Br)C=CC=C1)=O)C2=C(O)C=C(N(=O)=O)C=C2. References: White JR, et al. J Biol Chem. 1998, 273(17), 120095-120098.
| Anwendung: | CXCR2 antagonist |
| CAS | 182498-32-4 |
| MW: | 352.14 D |
ab 43,00 €
SB 225002
Artikelnummer: Cay13336-10
CXCR2 (IL-8RB) is a seven-transmembrane G protein-coupled receptor whose physiological ligands include IL-8 (CXCL8) and growth related oncogene alpha (Gro-alpha, CXCL1). IL-8 and Gro-alpha are pro-inflammatory CXC chemokines that act as chemoattractants, especially for neutrophils, and promote angiogenesis. SB...
| Schlagworte: | N-(2-bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)-urea |
| Anwendung: | CXCR2 antagonist |
| CAS | 182498-32-4 |
| MW: | 352.1 D |
ab 110,00 €
