Zu "1820787-94-7" wurden 2 Artikel gefunden!
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IRAK4-IN-1
Artikelnummer: TGM-T4140-100mg
Description: IRAK4-IN-1 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. Target: IRAK. Smiles: N#Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1. References: Smith GF, et al. Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation. Bioorg Med...
| Anwendung: | IRAK4 inhibitor |
| CAS | 1820787-94-7 |
| MW: | 337.42 D |
ab 64,00 €
IRAK4 Inhibitor 1
Artikelnummer: Cay37548-1
IRAK4 Inhibitor 1 (IRAK4-IN-1) is an inhibitor of IL-1 receptor-associated kinase 4 (IRAK4, IC50 = 7 nM). It reduces TNF-alpha level increases induced by the toll-like receptor 7 (TLR7) agonist resiquimod (R-848, Cay-14806) in isolated human peripheral blood mononuclear cells (PBMCs, EC50 = 300 nM).Formal Name:...
| Schlagworte: | IRAK4-IN-1, 4-[[trans-4-(4-morpholinyl)cyclohexyl]amino]-6-quinazolinecarbonitrile |
| Anwendung: | IRAK4 inhibitor |
| CAS | 1820787-94-7 |
| MW: | 337.4 D |
ab 78,00 €
