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PFI-3
Artikelnummer: TGM-T6939-100mg
Description: PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer. Target: Epigenetic Reader Domain. Smiles: [H][C@@]12CN(c3ccccn3)[C@@]([H])(CN1\C=C\C(=O)c1ccccc1O)C2. References: Structural Genomics Consortium...
| Schlagworte: | PFI 3 |
| Anwendung: | Bromodomain SMARCA4 / PB1 probe |
| CAS | 1819363-80-8 |
| MW: | 321.37 D |
ab 33,00 €
PFI-3
Artikelnummer: Cay15267-10
The SWI/SNF-related, Matrix-associated, Actin-dependent Regulator of Chromatin (SMARC) proteins integrate into complexes that remodel chromatin. The SMARC family A (SMARCA) members SMARCA2 (also known as BRM) and SMARCA4 (BRG1) are helicases that contain structurally-related bromodomains for binding acetylated...
| Schlagworte: | (2E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-(2-pyridinyl)-2,5-diazabicyclo[2.2.1]hept-2-yl]-2-propen-1-one |
| Anwendung: | Bromodomain SMARCA4 / PB1 probe |
| CAS | 1819363-80-8 |
| MW: | 321.4 D |
ab 44,00 €
PFI-3
Artikelnummer: BPS-82070
PFI-3 is a selective chemical probe for SMARCA bromodomains that inhibits SMARCA2, SMARCA4 and PB1(5) bromodomains. PFI-3 is a probe that binds avidly to the structurally-similar SMARCA4 bromodomain and PB1(bromodomain 5) with Kd values of 89 and 48 nM, respectively. PFI-3 displays 30-fold selectivity over other...
| Schlagworte: | PFI3, PFI 3, |
| Anwendung: | Bromodomain SMARCA4 / PB1 probe |
| CAS | 1819363-80-8 |
| MW: | 321,4 D |
752,00 €
