Zu "1818885-28-7" wurden 4 Artikel gefunden!
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ARV-825
Artikelnummer: TGM-T5434-100mg
Description: ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested. Target: Epigenetic Reader Domain, PROTACs. Smiles:...
| Anwendung: | Protac(R) reagent |
| CAS | 1818885-28-7 |
| MW: | 923.43 D |
ab 60,00 €
ARV-825
Artikelnummer: Cay21109-1
ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology. ARV-825 actively recruits BRD4 to cereblon, resulting in the rapid and efficient degradation of BRD4 by the proteasome (50%...
| Schlagworte: | 2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-(2-(2-(2-((2-(... |
| Anwendung: | BRD4 degradation |
| CAS | 1818885-28-7 |
| MW: | 923.4 D |
ab 67,00 €
ARV-825
Artikelnummer: LKT-A706840.1
| Schlagworte: | ARV825, SCHEMBL17162093, RWLOGRLTDKDANT-TYIYNAFKSA-N, BCP19950, CS-4776,... |
| Anwendung: | BRD4 degradation |
| CAS | 1818885-28-7 |
| MW: | 923.44 D |
ab 138,00 €
ARV-825
Artikelnummer: BPS-82035
ARV-825 is a PROTAC molecule composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety. ARV-825 recruits BRD4 to E3 ubiquitin ligase cereblon, resulting in the degradation of BRD4.
| Anwendung: | Protac(R) reagent |
| CAS | 1818885-28-7 |
| MW: | 923,5 D |
1.635,00 €
