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MM-206
MM-206

Artikelnummer: TGM-T28075-10mg

Description: MM-206, a cell-permeable, non-cytotoxic naphthalene sulfonamide compound, it effectively inhibits STAT3 DNA-binding activity. Target: Others. Smiles: N(S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F)C=2C3=C(C(O)=C(SC4=CC=CC=C4)C2)C=CC=C3
Anwendung: STAT3 inhibitor
CAS 1809581-87-0
MW: 497.46 D
ab 208,00 €
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MM-206
MM-206

Artikelnummer: Cay22032-10

MM-206 is an inhibitor of STAT3 (IC50 = 1.16 µM in an SPR-based competitive assay). It inhibits STAT3 phosphorylation induced by granulocyte colony-stimulating factor (G-CSF) in HL-60, Kasumi-1, and MOLM-13 acute myeloid leukemia (AML) cells (IC50s = 0.8, 1.9, and 1.1 µM, respectively). MM-206 induces apoptosis more...
Schlagworte: 2,3,4,5,6-pentafluoro-N-[4-hydroxy-3-(phenylthio)-1-naphthalenyl]-benzenesulfonamide
Anwendung: STAT3 inhibitor
CAS 1809581-87-0
MW: 497.5 D
ab 114,00 €
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