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ONO-8590580
Artikelnummer: TGM-TQ0040-100mg
Description: ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA alpha5. Target: GABA Receptor. Smiles: Cc1c(F)c(Nc2ccc(cn2)-c2cn(C)cn2)cc2n(CC3CC3)cnc12. References: Kawaharada S, et al. ONO-8590580, a Novel GABAAalpha5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves...
| Schlagworte: | CS-2894 |
| Anwendung: | Alpha5 subunit-containing GABAA receptor (benzodiazepine binding site) negative allosteric modulator |
| CAS | 1802661-73-9 |
| MW: | 376.43 D |
ab 59,00 €
ONO-8590580
Artikelnummer: Cay35297-10
ONO-8590580 is a negative allosteric modulator of alpha5 subunit-containing GABAA receptors that binds at the benzodiazepine binding site. It binds to alpha1, alpha2, alpha3, and alpha5 subunit-containing GABAA receptors (Kis = 140, 32, 24, and 7.9 nM, respectively). It is selective for inhibiting GABA-induced...
| Schlagworte: | 1-(cyclopropylmethyl)-5-fluoro-4-methyl-N-[5-(1-methyl-1H-imidazol-4-yl)-2-pyridinyl]-1H-benzimidazol-6-amine |
| Anwendung: | Alpha5 subunit-containing GABAA receptor (benzodiazepine binding site) negative allosteric modulator |
| CAS | 1802661-73-9 |
| MW: | 376.4 D |
ab 121,00 €
