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Brensocatib
Artikelnummer: TGM-TQ0038-10mg
Description: Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively). Target: Proteasome. Smiles: Cn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1. References: Doyle K, et al. Discovery of Second...
| Schlagworte: | AZD7986, INS 1007 |
| Anwendung: | Targets cathepsin C [EC:3.4.14.1] (CTSC) |
| CAS | 1802148-05-5 |
| MW: | 420.46 D |
ab 67,00 €
AZD 7986
Artikelnummer: Cay33184-10
AZD 7986 is a reversible and covalent inhibitor of dipeptidyl peptidase 1 (DPP-1), also known as cathepsin C (IC50 = 3.9 nM). It is selective for DPP-1 over cathepsins S, -L, -B, -K, -D, -E, -Z, -H, and -G (IC50s = >20 µM for all), as well as a panel of greater than 200 enzymes, receptors, ion channels, and...
| Schlagworte: | Brensocatib, INS1007,... |
| Anwendung: | CTSC inhibitor |
| CAS | 1802148-05-5 |
| MW: | 420.5 D |
ab 117,00 €
