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SB-224289 hydrochloride
SB-224289 hydrochloride

Artikelnummer: TGM-T12841-10mg

Description: SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect. Target: 5-HT Receptor. Smiles: Cl.CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1. References: Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine...
Schlagworte: SB-224289A
Anwendung: 5-HT1B inverse agonist
CAS 180084-26-8
MW: 557.08 D
ab 50,00 €
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SB-224289 (hydrochloride)
SB-224289 (hydrochloride)

Artikelnummer: Cay17036-5

The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine, 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-224289 is a potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold selectivity for human 5-HT1B over all other 5-HT receptors. It has been used to study the...
Schlagworte: [2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl](2,5,6,7-tetrahydro-1'-methylspiro[3H-furo[2,3-f]indole-...
Anwendung: 5-HT1B inverse agonist
CAS 180084-26-8
MW: 557.1 D
ab 78,00 €
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