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Centrinone
Artikelnummer: TGM-T14927-100mg
Description: Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4, Ki:0.16 nM). Target: Aurora Kinase, PLK. Smiles: COc1c(Nc2cc(C)[nH]n2)nc(Sc2ccc(cc2F)S(=O)(=O)Cc2cccc(c2F)[N+]([O-])=O)nc1N1CCOCC1. References: Wong YL. et al. Cell biology. Reversible centriole depletion with an...
| Schlagworte: | LCR-263 |
| Anwendung: | Plk4 inhibitor |
| CAS | 1798871-30-3 |
| MW: | 633.65 D |
ab 55,00 €
Centrinone
Artikelnummer: Cay24684-1
Centrinone is an inhibitor of polo-like kinase 4 (Plk4, Ki = 0.16 nM). It is greater than 1,100- and 2,800-fold selective for Plk4 over Aurora A and Aurora B kinases, respectively, and a panel of 442 kinases at 100 nM. Centrinone (125 nM) depletes centrosomes and induces apoptosis in HeLa cells.Formal Name:...
| Schlagworte: | LCR-263,... |
| Anwendung: | Plk4 inhibitor |
| CAS | 1798871-30-3 |
| MW: | 633.6 D |
ab 44,00 €
