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GSK-J4 Hydrochloride
Artikelnummer: TGM-T4383-100mg
Description: GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 µM in vitro. Target: Histone Demethylase. Smiles: Cl.CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1....
| Schlagworte: | GSK J4 HCl, GSK J4 HCl (1373423-53-0 free base) |
| Anwendung: | Histone demethylase inhibitor |
| CAS | 1797983-09-5 |
| MW: | 453.97 D |
ab 34,00 €
GSK-J4 (hydrochloride)
Artikelnummer: Cay12073-5
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J4 (hydrochloride) is an ethyl ester derivative of the JMJD3 selective histone demethylase inhibitor GSK-J1 (Cay-12054) with an...
| Schlagworte: | N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine, ethyl ester, monohydrochloride |
| Anwendung: | Histone demethylase inhibitor |
| CAS | 1797983-09-5 |
| MW: | 454 D |
ab 77,00 €
