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PD150606
Artikelnummer: TGM-T3525-1mg
Description: PD150606 is a selective nonpeptide calpain inhibitor with neuroprotective activity that inhibits µ-calpains and m-calpains. Inhibits erythrocyanine-induced Ca2+ efflux and interferes with excitotoxicity-dependent motor neuron death. Target: Cysteine Protease. Smiles: OC(=O)C(\S)=C\c1ccc(I)cc1....
| Anwendung: | Calpain inhibitor |
| CAS | 179528-45-1 |
| MW: | 306.12 D |
ab 31,00 €
PD 150606
Artikelnummer: Cay13859-5
The calpains are a family of calcium-dependent cysteine proteases which catalyze limited proteolysis of substrates. PD 150606 is a selective, cell-permeable inhibitor of calpains (Ki = 0.21 µM for µ-calpain (calpain-1) and 0.37 µM for m-calpain (calpain-2)). PD 150606 is commonly used to elucidate the roles for...
| Schlagworte: | 3-(4-iodophenyl)-2Z-mercapto-2-propenoic acid |
| Anwendung: | Calpain inhibitor |
| CAS | 179528-45-1 |
| MW: | 306.1 D |
ab 116,00 €
