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PD 168568 dihydrochloride
Artikelnummer: TGM-T12383-100mg
Description: PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM). Target: Dopamine Receptor. Smiles: O=C1NC(CCN2CCN(CC2)C3=CC=C(C)C(C)=C3)C4=C1C=CC=C4.Cl.Cl. References: Belliotti TR, et al. Isoindolinone enantiomers having...
| Schlagworte: | PD 168568 (dihydrochloride) |
| Anwendung: | Dopamine D4 receptor antagonist |
| CAS | 1782532-06-2 |
| MW: | 422.39 D |
ab 34,00 €
PD 168568 (hydrochloride)
Artikelnummer: Cay35483-1
PD 168568 is a dopamine D4 receptor antagonist (Ki = 8.8 nM). It is selective for dopamine D4 over D2 receptors (Ki = 1,842 nM). PD 168568 (3 mg/kg) reverses amphetamine-induced hyperlocomotion in rats. It also inhibits the growth of glioblastoma neural stem cells when used at concentrations of 25 and 50 µM.Formal...
| Schlagworte: | 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-one, dihydrochloride |
| Anwendung: | Dopamine D4 receptor antagonist |
| CAS | 1782532-06-2 |
| MW: | 422.4 D |
ab 44,00 €
