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S 18986
Artikelnummer: TGM-T16816-10mg
Description: S 18986 is a selective, orally active, brain-penetrant positive allosteric modulator of AMPA-type receptors that enhances cognition in rodents by inducing the release of noradrenaline and acetylcholine in the rat hippocampus, subsequently improving object-recognition memory. Target: GluR. Smiles:...
| Anwendung: | Glutamate ionotropic receptor positive allosteric modulator |
| CAS | 175340-20-2 |
| MW: | 224.28 D |
ab 31,00 €
S18986
Artikelnummer: Cay14937-1
S18986 is a positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that potently enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S18986 is orally bioavailable and penetrates the blood-brain barrier in animals....
| Schlagworte: | 2,3,3aS,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine, 5,5-dioxide |
| Anwendung: | Glutamate ionotropic receptor positive allosteric modulator |
| CAS | 175340-20-2 |
| MW: | 224.3 D |
ab 44,00 €
