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CD2665
Artikelnummer: TGM-T14911-10mg
Description: CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARgamma and RARbeta, the Kis are 110 nM and 306 nM. Target: Retinoid Receptor. Smiles: COCCOCOc1cc2ccc(cc2cc1C12CC3CC(CC(C3)C1)C2)-c1ccc(cc1)C(O)=O. References: Kim MJ, et al. The role of specific retinoid receptors in sebocyte...
| Anwendung: | RAR beta / gamma antagonist |
| CAS | 170355-78-9 |
| MW: | 486.6 D |
ab 81,00 €
CD2665
Artikelnummer: Cay16031-1
CD2665 is a selective retinoic acid receptor (RAR)beta and RARgamma antagonist (Kds = 110, 306, and > 2,250 nM for RARgamma, RARbeta, and RARalpha, respectively, with no binding at RXRalpha). At 10-7 M, it has been used to abrogate retinoic acid (Cay-11017)-induced antiproliferative and antidifferentiative effects...
| Schlagworte: | 4-[6-[(2-methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl]-benzoic acid |
| Anwendung: | RAR beta / gamma antagonist |
| CAS | 170355-78-9 |
| MW: | 486.6 D |
ab 50,00 €
