Zu "1700693-08-8" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
JH-II-127
Artikelnummer: TGM-T7155-100mg
Description: JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively. Target: LRRK2. Smiles: CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12. References: Discovery of a...
| Anwendung: | LRRK2 inhibitor |
| CAS | 1700693-08-8 |
| MW: | 416.86 D |
ab 45,00 €
JH-II-127
Artikelnummer: Cay22905-5
JH-II-127 is an orally bioavailable inhibitor of wild-type (WT) and mutant forms of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, as well as LRRK2 containing the G2019S and A2016T substitution mutations (IC50s = 6.6, 2.2, and 47.7 nM, respectively), which are present in certain patients with...
| Schlagworte: | [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone |
| Anwendung: | LRRK2 inhibitor |
| CAS | 1700693-08-8 |
| MW: | 416.9 D |
ab 44,00 €
JH-II-127
Artikelnummer: LKT-J291331.1
| Schlagworte: | Pyrrolopyrimidine |
| Anwendung: | LRRK2 inhibitor |
| CAS | 1700693-08-8 |
| MW: | 416.87 D |
ab 85,00 €
