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BAY-545
Artikelnummer: TGM-T8512-100mg
Description: BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM). Target: Adenosine Receptor. Smiles: CCn1c(=O)n(CCC(F)(F)F)c2sc(C(=O)N3CCC(O)CC3)c(C)c2c1=O. References: Härter M, et al. Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure. Eur J Med Chem. 2019 Feb...
| Anwendung: | Adenosine A2B receptor antagonist |
| CAS | 1699717-32-2 |
| MW: | 433.45 D |
ab 81,00 €
BAY-545
Artikelnummer: Cay28420-1
BAY-545 is an adenosine A2B receptor antagonist. It is selective for adenosine A2B receptors over A1, A2A, and A3 receptors with IC50 values of 66, 1,300, 820, and >6,700 nM, respectively, in CHO cell membranes expressing human recombinant receptors. BAY-545 reduces increases in the levels of IL-6 induced by the...
| Schlagworte: | 3-ethyl-6-[(4-hydroxy-1-piperidinyl)carbonyl]-5-methyl-1-(3,3,3-trifluoropropyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione |
| Anwendung: | Adenosine A2B receptor antagonist |
| CAS | 1699717-32-2 |
| MW: | 433.4 D |
217,00 €
