Zu "167869-21-8" wurden 5 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
PD 98059
Artikelnummer: Cay10006726-1
PD 98059 is a noncompetitive inhibitor of the MAPK pathway. It prevents the activation of MEK by Raf or MEK kinase (a MAP3K) with an IC50 value of 2-7 µM but does not inhibit Raf-activated MAP2K1. It inhibits Raf activation of MAP2K2 with an IC50 value of 50 µM. PD 98059 also phosphorylates and activates...
| Schlagworte: | NSC 679828, 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | MAPK inhibitor |
| CAS | 167869-21-8 |
| MW: | 267.3 D |
ab 26,00 €
MEK1 Inhibitor (PD98059),
Artikelnummer: M2865-17A.5
PD98059 (MEK1 Inhibitor) has been shown to act in vivo as a highly selective inhibitor of MEK1 activation and the MAP kinase cascade (1-4). PD98059 binds to the inactive forms of MEK1 and prevents activation by upstream activators such as c-Raf (3), Specificity: Inhibits activation of MEK1 and MEK2 with IC50 values...
| Anwendung: | WB |
| CAS | 167869-21-8 |
| MW: | 267.28 D |
ab 311,00 €
PD 98,059
Artikelnummer: AG-CR1-0118-M010
Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells.
| Schlagworte: | 2'-Amino-3'-methoxyflavone |
| Anwendung: | MEK inhibitor |
| CAS | 167869-21-8 |
| MW: | 267,3 D |
ab 22,00 €
MEK1 Inhibitor (PD98059, 2+-amino-3+-methoxyflavone)
Artikelnummer: M2865-17B.5
PD98059 is a potent and selective cell permeable inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK, thereby inhibiting the phosphorylation and the activation of MAP kinase. In pheochromocytoma (PC12) cells, it completely blocks the increase in MAP kinase activity produced by NGF....
| CAS | 167869-21-8 |
| MW: | 267.00 kD |
537,00 €
MEK1 Inhibitor (PD98059, 2'-amino-3'-methoxyflavone)
Artikelnummer: M2865-17C.5
Potent, selective and cell-permeable inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). Inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself. IC50 values for PD 98059-induced effects are in the 1-20uM range for many assays, it is...
| CAS | 167869-21-8 |
| MW: | 267.28 |
220,00 €
